Accepted articles

Conferences and symposia


Current physics research challenges in radiation medicine

 a, b,  a, b, c,  a, b,  a, b,  a, b,  a, b,  b, d,  a, d,  a, c,  b,  a, e,  a, f,  g,  a, b
a Lomonosov Moscow State University, Faculty of Physics, Leninskie Gory 1 build. 2, Moscow, 119991, Russian Federation
b Lomonosov Moscow State University, Skobeltsyn Institute of Nuclear Physics, Leninskie Gory 1 build. 2, Moscow, 119991, Russian Federation
c GBUZ Moscow Clinical Scientific Center named after Loginov MHD, Shosse Entuziastov 86, Moscow, 111123, Russian Federation
d Federal Research Center of Pediatric Hematology, Oncology and Immunology, ul. Samory Mashela 1, Moscow, 117997, Russian Federation
e Gamma Knife Center JSC Business Center for Neurosurgery, 4 Tverskaya-Yamskaya str., Moscow, 125047, Russian Federation
f State budgetary Institution of Healthcare of the Moscow City Scientific and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Department of Health, Petrovka str. 24, bld. 1, Moscow, 127051, Russian Federation
g FSBI Federal Scientific Clinical Center for Medical Radiology and Oncology of FMBA of Russia, Kurchatova Str. 5v, Dimitrovgrad, Ulyanovsk Region, 433506, Russian Federation

This review discusses the fundamental physical concepts being developed by physicists and medical researchers to improve existing and create new high-technology radiation-based methods for cancer treatment. It presents a broad overview of current research in the physics of radiation technologies for medicine, including approaches to advancing radiation therapy and imaging using photon, electron, and proton beams, the integration of artificial intelligence into these technologies, and the development of novel methods for radiation dose verification and monitoring. These approaches, founded on innovative physical principles, are currently being developed and translated into clinical practice in radiation therapy and diagnostic imaging. The review describes the underlying physical principles of these technologies and discusses their prospects for future application in the treatment of cancer patients. It also highlights the role of Moscow State University in advancing a wide range of world-class research in radiation medicine through collaboration with scientists and clinicians from leading oncology institutions.

Keywords: radiation, dose, radiation therapy, diagnostic imaging, nuclear medicine
PACS: 87.19.xj, 87.55.−x, 87.56.−v (all)
DOI: 10.3367/UFNe.2026.03.040160
Citation: Chernyaev A P, Lykova E N, Studenikin F R, Shcherbakov A A, Kim A A, Zheltonozhskaya M V, Loginova A A, Zharkova A P, Kopilova E A, Kobyakova T A, Novikova E A, Kublinskaya Yu A, Kiselev V A, Adoniev S R "Current physics research challenges in radiation medicine" Phys. Usp., accepted

25th, March 2026

Оригинал: Черняев А П, Лыкова Е Н, Студеникин Ф Р, Щербаков А А, Ким А А, Желтоножская М В, Логинова А А, Жаркова А П, Копылова Е А, Кобякова Т А, Новикова Е А, Кублинская Ю А, Киселев В А, Адоньев С Р «Актуальные физические научные задачи для радиационной медицины» УФН, принята к публикации; DOI: 10.3367/UFNr.2026.03.040160

Similar articles (20) ↓

  1. A.P. Chernyaev, E.N. Lykova et al “Radiation medical physics” Phys. Usp. 69 (7) (2026)
  2. I.N. Zavestovskaya, S.M. Deyev et al “History, current status, and prospects for the development of boron neutron capture therapy” Phys. Usp. 69 (7) (2026)
  3. S.V. Akulinichev “Promising nuclear medicine research in the Institute of Nuclear Research, Russian Academy of Sciences” Phys. Usp. 57 1239–1243 (2014)
  4. B.L. Zhuikov “Success and problems in development of medical radioisotope production in Russia” Phys. Usp. 59 481–486 (2016)
  5. L.V. Kravchuk “Development of nuclear physics medicine at the Institute for Nuclear Research, RAS” Phys. Usp. 53 635–639 (2010)
  6. M.Yu. Azarkin, I.N. Zavestovskaya et al “Modeling the mechanisms of ionizing radiation damage to living tissue structures in radiotherapy technologies” Phys. Usp., accepted
  7. D.I. Iudin, S.S. Davydenko et al “Physics of lightning: new model approaches and prospects of the satellite observations” Phys. Usp. 61 766–778 (2018)
  8. V.P. Filonenko, I.P. Zibrov et al “Diamond-based superhard composites: new synthesis approaches and application prospects” Phys. Usp. 62 207–212 (2019)
  9. “Physical methods for biomedicine (Scientific Session of the Physical Sciences Division of the Russian Academy of Sciences, March 25, 2026)” Phys. Usp., accepted
  10. L.E. Vorob’ev, D.A. Firsov et al “The outlook for the development of radiation sources in the middle-IR range based on the intraband transitions between the energy levels of charge carriers in injection laser heterostructures with quantum dots and wells” Phys. Usp. 42 391–396 (1999)
  11. L.M. Zelenyi “Prospects for the development of fundamental physics and astronomy (Scientific session of the general meeting of the Physical Sciences Division of the Russian Academy of Sciences, 15 December 2008)” Phys. Usp. 52 1055–1055 (2009)
  12. M.Yu. Romanovskii “Laser radiation enhancement of forbidden orbital electron captures and of neutrinoless double electron captures by nuclei” Phys. Usp. 55 728–733 (2012)
  13. I.Yu. Kostyukov, A.M. Pukhov “Plasma-based methods for electron acceleration: current status and prospects” Phys. Usp. 58 81–88 (2015)
  14. V.N. Rudenko “Gravitational-wave experiment in Russia” Phys. Usp. 60 830–842 (2017)
  15. D.B. Abramenko, P.S. Antsiferov et al “Plasma-based sources of extreme ultraviolet radiation for lithography and mask inspection” Phys. Usp. 62 304–314 (2019)
  16. V.V. Vlasyuk, I.V. Afanasieva et al “Large-format imaging systems based on solid-state detectors in optical astronomy” Phys. Usp. 67 405–416 (2024)
  17. “The Physical Sciences Division of the Russian Academy of Sciences on solving problems related to scientific and technological development of the Russian Federation (Scientific Session of the General Meeting of the Physical Sciences Division of the Russian Academy of Sciences (P.N. Lebedev Physical Institute of the Russian Academy of Sciences, December 9, 2024))” Phys. Usp. 68 551–551 (2025)
  18. M.Yu. Glyavin, G.G. Denisov et al “High power terahertz sources for spectroscopy and material diagnostics” Phys. Usp. 59 595–604 (2016)
  19. V.N. Tsytovich “Polarization effects in a medium: from Vavilov-Cherenkov radiation and transition radiation to dust-particle pairing, or the development of one of V L Ginzburg’s ideas from 1940 to 2006” Phys. Usp. 50 545–553 (2007)
  20. K.N. Koshelev, V.E. Banine, N.N. Salashchenko “Research and development in short-wave radiation sources for new-generation lithography” Phys. Usp. 50 741–744 (2007)

The list is formed automatically.

© 1918–2026 Uspekhi Fizicheskikh Nauk
Email: ufn@ufn.ru Editorial office contacts About the journal Terms and conditions