Quantum processes in biological molecules. Enzyme catalysis

The oxidation-reduction enzymatic reaction is treated as a nonadiabatic multiquantum transition from the initial substrate-enzyme complex to a free product and free enzyme, taking into account the contribution of low-frequency (conformational) degrees of freedom of the enzyme molecule to the quantum transition described in terms of the reaction coordinate. It is demonstrated that the electromagnetic field has a marked effect on the enzymatic reaction rate by exciting low-frequency vibrations of enzyme molecules, a fact from which the nature of the so-called narrow biological resonances may be understood. A new mechanism giving rise to ultraviolet radiation from biological membranes is discussed. The theory can be used to explain the origin of ultraviolet radiation and dipole ordering of globular cell proteins.

PACS: 33.80.Rv, 87.10.+e, 87.15.−v, 82.50.−m (all)
DOI: 10.1070/PU1999v042n08ABEH000480
URL: https://ufn.ru/en/articles/1999/8/c/
Web of Science

000083411000003
Citation: Kovarskii V A "Quantum processes in biological molecules. Enzyme catalysis" Phys. Usp. 42 797–815 (1999)

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Оригинал: Коварский В А «Квантовые процессы в биологических молекулах. Ферментативный катализ» УФН 169 889–908 (1999); DOI: 10.3367/UFNr.0169.199908c.0889

References (89) Cited by (25) Similar articles (20) ↓

V.N. Binhi, A.V. Savin “Effects of weak magnetic fields on biological systems: physical aspects” 46 259–291 (2003)
M.D. Frank-Kamenetskii, A.V. Lukashin “Electron-vibrational interactions in polyatomic molecules” 18 391–409 (1975)
D.S. Chernavskii “The origin of life and thinking from the viewpoint of modern physics” 43 151–176 (2000)
Ya.B. Zel’dovich, A.L. Buchachenko, E.L. Frankevich “Magnetic-spin effects in chemistry and molecular physics” 31 385–408 (1988)
F.V. Bunkin, N.A. Kirichenko, B.S. Luk’yanchuk “Thermochemical action of laser radiation” 25 662–687 (1982)
V.S. Letokhov “Selective action of laser radiation on matter” 21 405–428 (1978)
G.N. Makarov “Selective processes of IR excitation and dissociation of molecules in gasdynamically cooled jets and flows” 48 37–76 (2005)
N.G. Basov, O.N. Krokhin, Yu.M. Popov “Generation, amplification, and detection of infrared and optical radiation by quantum-mechanical systems” 3 702–728 (1961)
A.A. Puretskii, V.V. Tyakht “Inverse electronic relaxation in the case of multiphoton excitation of molecules by infrared laser radiation” 32 30–50 (1989)
R.A. Avarmaa, K.K. Rebane “Zero-phonon lines in the spectra of chlorophyll-type molecules embedded in low-temperature solid-state matrices” 31 225–240 (1988)
V.S. Antonov, V.S. Letokhov, A.N. Shibanov “Laser resonance photoionization spectroscopy of molecules” 27 81–105 (1984)
N.B. Delone, V.A. Kovarskii et al “An atom in the radiation field of a multifrequency laser” 23 472–492 (1980)
K.A. Valiev “Quantum computers and quantum computations” 48 1–36 (2005)
G.R. Ivanitskii, A.B. Medvinskii et al “From Maxwell’s demon to the self-organization of mass transfer processes in living systems” 41 1115–1126 (1998)
A.Yu. Grosberg “Disordered polymers” 40 125–158 (1997)
B.U. Barshchevskii “Exciton photochemistry of light-sensitive crystals” 44 397–414 (2001)
Yu.F. Krupyanskii, V.I. Gol’danskii “Dynamical properties and energy landscape of simple globular proteins” 45 1131–1151 (2002)
I.Sh. Averbukh, N.F. Perel’man “The dynamics of wave packets of highly-excited states of atoms and molecules” 34 (7) 572–591 (1991)
V.E. Ostrovskii, E.A. Kadyshevich “Generalized hypothesis of the origin of the living-matter simplest elements, transformation of the Archean atmosphere, and the formation of methane-hydrate deposits” 50 175–196 (2007)
Yu.M. Romanovsky, A.N. Tikhonov “Molecular energy transducers of the living cell. Proton ATP synthase: a rotating molecular motor” 53 893–914 (2010)

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