Issues

 / 

2010

 / 

September

  

Reviews of topical problems


Molecular energy transducers of the living cell. Proton ATP synthase: a rotating molecular motor

,
Lomonosov Moscow State University, Department of Physics, Vorobevy gory, Moscow, 119992, Russian Federation

The free energy released upon the enzymatic hydrolysis of adenosine triphosphate (ATP) is the main source of energy for the functioning of the living cell and all multicellular organisms. The overwhelming majority of ATP molecules are formed by proton ATP synthases, which are the smallest macromolecular electric motors in Nature. This paper reviews the modern concepts of the molecular structure and functioning of the proton ATP synthase, and real-time biophysical experiments on the rotation of the ’rotor’ of this macromolecular motor. Some mathematical models describing the operation of this nanosized macromolecular machine are described.

Text can be downloaded in Russian. English translation is available on IOP Science.
PACS: 87.10.−e, 87.15.−v, 87.16.−b (all)
DOI: 10.3367/UFNe.0180.201009b.0931
URL: https://ufn.ru/en/articles/2010/9/b/
Citation: Romanovsky Yu M, Tikhonov A N "Molecular energy transducers of the living cell. Proton ATP synthase: a rotating molecular motor" Phys. Usp. 53 893–914 (2010)
BibTexBibNote ® (generic)BibNote ® (RIS)MedlineRefWorks

Оригинал: Романовский Ю М, Тихонов А Н «Молекулярные преобразователи энергии живой клетки. Протонная АТФ-синтаза — вращающийся молекулярный мотор» УФН 180 931–956 (2010); DOI: 10.3367/UFNr.0180.201009b.0931

References (142) Cited by (30) Similar articles (20)

© 1918–2019 Uspekhi Fizicheskikh Nauk
Email: ufn@ufn.ru Editorial office contacts About the journal Terms and conditions