Issues

 / 

2026

 / 

July

←  →

Conferences and symposia


Radiation medical physics

† , , , , ,
Lomonosov Moscow State University, Vorobevy Gory, Moscow, 119991, Russian Federation

This review presents the origin, development, and objectives of the new field of "Radiation Medical Physics." The fundamental physical ideas underlying high-tech medical methods for the treatment of oncological malignancies and some of the most relevant areas of fundamental research in the field of radiation technologies for medicine are discussed. The results of joint work conducted by Moscow University and leading oncology centers in Moscow and Russia, which have gained wide recognition and are used to treat patients, are shown. The only Russian multi-stage system for training medical physicists working in radiotherapy departments of oncology centers and the role of Moscow University in the development of this educational and scientific field are described.

Typically, an English full text is available in about 1 month from the date of publication of the original article.

Correspondence should be addressed to
Keywords: radiation, dose, radiotherapy, nuclear medicine, radionuclide diagnostics, therapeutic interval
PACS: 87.19.xj, 87.55.−x, 87.56.−v (all)
DOI: 10.3367/UFNe.2025.05.040012
URL: https://ufn.ru/en/articles/2026/7/c/
Citation: Chernyaev A P, Lykova E N, Studenikin F R, Shcherbakov A A, Kim A A, Zheltonozhskaya M V "Radiation medical physics" Phys. Usp. 69 (7) (2026)

Received: 8th, August 2025, 21st, May 2025

Оригинал: Черняев А П, Лыкова Е Н, Студеникин Ф Р, Щербаков А А, Ким А А, Желтоножская М В «Радиационная медицинская физика» УФН 196 708–725 (2026); DOI: 10.3367/UFNr.2025.05.040012

References (123) ↓ Cited by (1) Similar articles (20)

  1. Röntgen W C Science 3 227 (1896)
  2. Becquerel H C. R. Hebdomadaires Seances Acad. Sci. 122 420 (1896)
  3. Grubbe E H Medical Record 62 692 (1902)
  4. Curie P, Sklodowska-Curie M C. R. Acad. Sci. 127 1215 (1898)
  5. van’t Riet A et al Int. J. Radiat. Oncol. Biol. Phys. 37 731 (1997)
  6. Zimmermann R Nuclear Medicine: Radioactivity For Diagnosis And Therapy (Les Ulis: EDP Sciences, 2007)
  7. Foray N Int. J. Radiat. Oncol. Biol. Phys. 96 717 (2016)
  8. Brierley J, Sherman E Seminars Radiat. Oncol. 22 254 (2012)
  9. Lister G D, Gibson T Br. J. Plast. Surg. 26 328 (1973)
  10. Goodman P C Am. J. Roentgenol. 165 1046 (1995)
  11. Huh H D, Kim S Prog. Med. Phys. 31 124 (2020)
  12. Colvett K South Med. J. 99 1155 (2006)
  13. Christakis P Yale J. Biol. Med. 84 169 (2011)
  14. Mohamed M M, Sloane B F Nature Rev. Cancer 6 764 (2006)
  15. ’Fр’?с’?’?’?’? ’M ’B Usp. Fiz. Nauk 186 435 (2016); Krasavin E A Phys. Usp. 59 411 (2016)
  16. Crowther J A Proc. R. Soc. London B 100 390 (1926)
  17. Sievert R M Eine Methode Zur Messung Von Röntgen-, Radium Und Ultrastrahlung: Nebst Einige Untersuchungen über Die Anwendbarkeit Derselben In Der Physik Und Der Medizin, Mit Einem Anhang Enthaltend Einige Formeln Und Tabellen Für Die Berechnung Der Intensitätsverteilung Bei Gamma-Strahlungsquellen (Stockholm: Kungl. Boktryckeriet, P.A. Norstedt and Söner, 1932)
  18. Lea D E Actions Of Radiations On Living Cells (Cambridge: The Univ. Press, 1946)
  19. Coutard H Am. J. Roentgenol. 28 313 (1932)
  20. ’F’?’?’?’?’? ’I ’R, Kh’?р’?sh’?’?’? ’E ’l Usp. Fiz. Nauk 186 891 (2016); Klenov G I, Khoroshkov V S Phys. Usp. 59 807 (2016)
  21. Grubbé E Radiology 21 156 (1933)
  22. Baltas D, Sakelliou L, Zamboglou N The Physics Of Modern Brachytherapy For Oncology (Boca Raton, FL: Taylor and Francis, 2007)
  23. ’a’?’?стр’?’?’?’? ’K ’v, ’Iр’?’?’?’? ’K ’B ’E’?’?р’?сы ’?’?’?’?’?’?’?’?’? 64 459 (2018)
  24. Sievert R M Acta Radiologica 1 89 (1921)
  25. Kh’?’?’?’?’? ’E Usp. Fiz. Nauk 3 99 (1922)
  26. Radiation Quantities and Units Intern. Commission on Radiological Units and Measurements (ICRU), Report 10a, Handbook 84 (Washington, DC: United States Department of Commerce National Bureau of Standards Library, 1962)
  27. Gray L H Proc. R. Soc. London A 156 578 (1936)
  28. Sievert R M Acta Radiol. 2 189 (1940)
  29. Webster J H D Proc. R. Soc. Med. 27 901 (1934)
  30. Coutard H The Lancet 224 1 (1934)
  31. Ginzton E L, Nunan C S Int. J. Radiat. Oncol. Biol. Phys. 11 205 (1985)
  32. McCready V R Eur. J. Nucl. Med. Mol. Imaging 44 179 (2017)
  33. Copeland D E, Benjamin E W Nucleonics 5 44 (1949)
  34. ’’’?’?’?’? ’E ’a, ’iу’?ya’?ts’?’? ’E ’E Atom. Energ. 25 449 (1968); Levin V M, Rumyantsev V V Sov. Atom. Energy 25 1271 (1968)
  35. Johns H E et al Nature 168 1035 (1951)
  36. Slater J M, Miller D W, Archambeau J O Int. J. Radiat. Oncol. Biol. Phys. 14 761 (1988)
  37. Larsson B et al Nature 182 1222 (1958)
  38. Alenitsky Y G et al Proc. Of The 20th Russian Conf. On Charged Particle Accelerators, RuPAC 2006, Novosibirsk, Russia, September 10-14, 2006 (Eds M Kuzin, E Shirkova) (Novosibirsk: BINP, 2006)
  39. ’R’?’?’?’?’? ’B ’B ’? ’?р Usp. Fiz. Nauk 192 893 (2022); Ivanov A A et al Phys. Usp. 65 834 (2022)
  40. Fowler J F British J. Radiol. 38 365 (1965)
  41. Hounsfield G N British J. Radiol. 46 1016 (1973)
  42. Ambrose J British J. Radiol. 46 1023 (1973)
  43. Leksell L Acta Chir. Scand. 134 585 (1968)
  44. Lauterbur P C Nature 242 190 (1973)
  45. Mansfield P J. Phys. C 55 (1977)
  46. McCullough E C, Krueger A M Int. J. Radiat. Oncol. Biol. Phys. 6 1599 (1980)
  47. Cunningham J R Int. J. Radiat. Oncol. Biol. Phys. 16 1367 (1989)
  48. Favaudon V et al Sci. Transl. Med. 6 245 (2014)
  49. ’Gу’?’?’?’?’? ’l ’E ’? ’?р Usp. Fiz. Nauk 184 1265 (2014); Bulanov S V et al Phys. Usp. 57 1149 (2014)
  50. ’Fр’?’?chу’? ’’ ’E Usp. Fiz. Nauk 180 665 (2010); Kravchuk L V Phys. Usp. 53 635 (2010)
  51. ’a’?т’?’?’?’? ’E ’B Usp. Fiz. Nauk 194 1250 (2024); Matveev V A Phys. Usp. 67 1180 (2024)
  52. ’B’?у’?’?’?’?ch’?’? ’l ’E Usp. Fiz. Nauk 184 1363 (2014); Akulinichev S V Phys. Usp. 57 1239 (2014)
  53. Ng J, Shuryak I Cancer Manag. Res. 7 1 (2014)
  54. Thwaites D, Baldock C J. Phys. Conf. Ser. 444 011001 (2013)
  55. Hall E J, Wuu C-S Int. J. Radiat. Oncol. Biol. Phys. 56 83 (2003)
  56. Chernyaev A et al Quantum Beam. Sci. 7 27 (2023)
  57. Kamran S C et al Cancer 122 1809 (2016)
  58. de Gonzalez A B et al Lancet Oncol. 12 353 (2011)
  59. Kim T J et al Cancers 13 1144 (2021)
  60. Atli E et al Diagnostic Intervent. Rad. 27 1147 (2021)
  61. Sodickson A et al Radiology 251 175 (2009)
  62. Dalah Z et al Clin. Pract. 14 1550 (2024)
  63. Cao C-F et al BMC Cancer 22 1238 (2022)
  64. Nievelstein R A J et al Eur. Radiol. 22 1946 (2012)
  65. Verfaillie G et al EJNMMI Phys. 10 32 (2023)
  66. Brix G et al Eur. J. Nucl. Med. Mol. Imaging 41 S125 (2014)
  67. Grewal R K et al J. Nucl. Med. 51 1361 (2010)
  68. Huang B, Law M W M, Khong P L Radiology 251 166 (2009)
  69. Alshamrani A F A, Alrehily F A JRRAS 18 101303 (2025)
  70. Murat H et al Radioprotection 60 65 (2025)
  71. Fabritius G et al Sci. Rep. 6 35181 (2016)
  72. Schöder H, Gönen M Nucl. Med. 4 18 (2007)
  73. Ben-Sellem D, Ben-Rejeb N Nucl. Med. Mol. Imaging 55 173 (2021)
  74. Hosono M et al British J. Radiol. 94 1126 (2021)
  75. Chawla S C et al Pediatr. Radiol. 40 681 (2010)
  76. ’’ы’?’?’?’? ’M ’v ’? ’?р ’E’?ст’?. ’a’?с’?. у’?-т’?. ’l’?р. 3 ’s’?’?. ’Bстр’?’?. (4) 2440703 (2024); Lykova E N et al Moscow Univ. Phys. Bull. 79 524 (2024)
  77. Torfeh T et al Magn. Reson. Imaging 34 645 (2016)
  78. Jezzard P Neuroimage 62 648 (2012)
  79. Lu L et al J. Appl. Clin. Med. Phys. 24 e13843 (2023)
  80. Wang D, Doddrell D M Curr. Med. Imaging. Rev. 1 49 (2005)
  81. ’I’?’?ts’?’?с’?’?’? ’z ’z ’? ’?р Izv. Ross. Akad. Nauk. Fiz. 84 1547 (2020)
  82. Chernyaev A P, Lykova E N, Shcherbakov A A Nanobiotechnol. Rep. 18 617 (2023)
  83. ’’ы’?’?’?’? ’M ’v "’Rсс’?’?’?’?’?’?’?’?’? ’?’?т’?’?’?’? ’?т’?р’?ch’?ыkh ch’?ст’?ts ’?р’? р’?’?’?т’? ’?’?’?’?ts’?’?с’?’?’?’? ус’?’?р’?т’?’?ya с э’?’?р’?’?’?’? 18-20 ’aэ’E" ’K’?сс. ... ’?’?’?’?. ф’?’?.-’?’?т. ’?’?у’? (’a.: ’a’I’p ’?’?’?’?’? ’a.’E. ’’’?’?’?’?’?с’?’?’?, 2019)
  84. Hall E J Int. J. Radiat. Oncol. Biol. Phys. 65 1 (2006)
  85. Romero-Expósito M, Toma-Dasu I, Dasu A Front. Oncol. 12 892078 (2022)
  86. Takam R et al Radiat. Res. 176 508 (2011)
  87. Kinoshita N et al Radiol. Phys. Technol. 18 58 (2025)
  88. Yock A D et al Pract. Radiat. Oncol. 9 200 (2019)
  89. Takahashi Y et al Sci. Rep. 15 3608 (2025)
  90. Du W et al J. Appl. Clin. Med. Phys. 17 167 (2016)
  91. Hansen E K et al Int. J. Radiat. Oncol. Biol. Phys. 64 355 (2016)
  92. Bortfeld T et al Phys. Med. Biol. 47 302 (2002)
  93. ’’ы’?’?’?’? ’M ’v ’? ’?р Izv. Ross. Akad. Nauk. Fiz. 86 557 (2022)
  94. National Research Council. 2006. Health Risks from Exposure to Low Levels of Ionizing Radiation: BEIR VII (Washington, DC: The National Academies Press, 2006)
  95. Li C I et al Cancer Res. 70 7187 (2010)
  96. Preston D L Cancer Spectrum Knowledge Environment 94 1555 (2002)
  97. Neglia J P et al J. Natl. Cancer Inst. 98 1528 (2006)
  98. ’Oу’?’?’?’? ’a ’B ’? ’?р Usp. Fiz. Nauk 189 1293 (2019); Zubkov M A et al Phys. Usp. 62 1214 (2019)
  99. Jena R et al Clin. Oncol. 17 581 (2005)
  100. Loginova A A et al Front. Oncol. 1 2 (2022)
  101. Belikhin M et al Phys. Med. 112 102612 (2023)
  102. ’O’?’?’?ст’?’?с’?’?ya ’R ’v, ’F’?’?’?’?’?’? ’B ’E, ’iya’?’?’? ’E ’B Usp. Fiz. Nauk 194 917 (2024); Zavestovskaya I N, Kolobov A V, Ryabov V A Phys. Usp. 67 866 (2024)
  103. ’G’?’?’?kh’?’? ’a ’B "’i’?’?р’?’?’?т’?’? ’? ’?сс’?’?’?’?’?’?’?’?’? ’?’?т’?’?’? ’?’?’?’?’?’?с’?ts’?’? ’?’?’?zh’?’?’?ya ’?’?уkh’?’?’?’? ’? ’?р’?т’?’?’?’?’? т’?р’?’?’?’? с’?’?’?’?руyushch’?’? ’?уch’?’?’?" ’K’?сс. ... ’?’?’?’?. ф’?’?.-’?’?т. ’?’?у’? (’a.: ’a’I’p ’?’?’?’?’? ’a.’E. ’’’?’?’?’?’?с’?’?’?, 2023)
  104. Zhу’?’?’?’? ’G ’’ Usp. Fiz. Nauk 186 544 (2016); Zhuikov B L Phys. Usp. 59 481 (2016)
  105. ’Kьyach’?’?’? ’B ’G ’? ’?р Usp. Fiz. Nauk 193 554 (2023); Dyachkov A B et al Phys. Usp. 66 518 (2023)
  106. Zheltonozhskaya M V et al Nanobiotechnol. Rep. 18 577 (2023)
  107. Zheltonozhsky V A et al Nucl. Instrum. Meth. Phys. Res. B 476 68 (2020)
  108. Zh’?’?т’?’?’?zhс’?’?’? ’E ’B ’? ’?р Izv. Ross. Akad. Nauk. Fiz. 84 1116 (2020); Zheltonozhsky V A et al Bull. Russ. Acad. Sci. Phys. 84 923 (2020)
  109. Zheltonozhsky V A et al Eur. Phys. J. A 57 121 (2021)
  110. Zh’?’?т’?’?’?zhс’?’?’? ’E ’B ’? ’?р Izv. Ross. Akad. Nauk. Fiz. 86 1305 (2022); Zheltonozhskiy V A et al Bull. Russ. Acad. Sci. Phys. 86 1083 (2022)
  111. Zh’?’?т’?’?’?zhс’?’?ya ’a ’E ’? ’?р ’z’?сь’?’? ’eCh’BYa 20 1471 (2023); Zheltonozhskaya M V et al Phys. Part. Nucl. Lett. 20 1433 (2023)
  112. Zh’?’?т’?’?’?zhс’?’?ya ’a ’E ’? ’?р Ya’?’?р’?’?ya ф’?’?’?’?’? 86 641 (2023); Zheltonozhskaya M V et al Phys. Atom. Nucl. 86 917 (2023)
  113. Koning A J, Rochman D Nucl. Data Sheets 113 2841 (2012)
  114. Kabasakal L et al Mol. Imaging Radionucl. Therapy 26 62 (2017)
  115. Zheltonozhskaya M V et al Radiat. Phys. Chem. 224 112082 (2024)
  116. ’i’?’?’?’?’?’? ’z ’K ’? ’?р Ya’?’?р’?’?ya ф’?’?’?’?’? 86 99 (2023); Remizov P D et al Phys. Atom. Nucl. 85 818 (2022)
  117. Zheltonozhskaya M V, Remizov P D, Chernyaev A P Appl. Radiat. Isotop. 199 110871 (2023)
  118. Remizov P D et al Eur. Phys. J. A 59 141 (2023)
  119. ’i’?’?’?’?’?’? ’z ’K ’? ’?р Izv. Ross. Akad. Nauk. Fiz. 87 1092 (2023); Remizov P D et al Bull. Russ. Acad. Sci. Phys. 87 1112 (2023)
  120. ’Gрya’?’?’?’? ’B ’B, ’Fу’?с’?’?’?’? ’v ’F, ’l’?’?’?’?’?’? ’i ’B Usp. Fiz. Nauk 188 672 (2018); Bryazgin A A, Kuksanov N K, Salimov R A Phys. Usp. 61 601 (2018)
  121. Nikolaeva N et al Int. J. Mol. Sci. 24 14426 (2023)
  122. Zolotov S A et al Phys. Scr. 100 045020 (2025)
  123. Shik A V et al Food Chem. 482 144073 (2025)

© 1918–2026 Uspekhi Fizicheskikh Nauk
Email: ufn@ufn.ru Editorial office contacts About the journal Terms and conditions