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Reviews of topical problems


Neurophotonics: optical methods to study and control the brain

 a, b,  a, b,  a, b,  c,  d, a, c, b, e
a Lomonosov Moscow State University, Vorobevy Gory, Moscow, 119991, Russian Federation
b International Center for Quantum Optics and Quantum Technologies (the Russian Quantum Center), Skolkovo Innovation Center, Bolshoi Boulevard, Building 30, Block 1, 3rd floor, sectors G3, G7, Moscow, Moscow Region, 121205, Russian Federation
c National Research Centre ‘Kurchatov Institute’, pl. akad. Kurchatova 1, Moscow, 123182, Russian Federation
d International Laser Center of M.V. Lomonosov Moscow State University, Vorobevy gory, Moscow, 119992, Russian Federation
e Texas A&M University, College Station, Texas, USA

Methods of optical physics offer unique opportunities for the investigation of brain and higher nervous activity. The integration of cutting-edge laser technologies and advanced neurobiology opens a new cross-disciplinary direction of natural sciences — neurophotonics, leading to the development of a vast arsenal of tools for functional brain diagnostics, stimulation of individual neurons and neural networks, as well as molecular engineering of brain cells aimed at a diagnosis and therapy of neurodegenerative and psychic diseases. Optical fibers suggest unique approaches helping to confront the most challenging problems in brain research, including the analysis of cellular and molecular mechanisms behind memory and cognition. Optical fibers of new generation offer new solutions for the development of fundamentally new, unique tools for neurophotonics and laser neuroengineering — fiber-optic neuroendoscopes and neurointerfaces. These instruments open new horizons for the investigation of the most complex brain functions, enabling a long-term multiplex detection of fluorescent protein markers, as well as photostimulation of neuronal activity in deep brain areas in living, freely behaving animals with an unprecedented spatial resolution and minimal invasiveness. This emerging technology opens new horizons for understanding learning and long-term memory through experiments with living, freely behaving mammals. Here, we offer a brief review of this rapidly growing field of research.

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Fulltext is also available at DOI: 10.3367/UFNe.0185.201504c.0371
Keywords: neurophotonics, fiber-optic probes, nonlinear-optical microscopy
PACS: 42.81.−i, 87.19.L−, 87.85.D− (all)
DOI: 10.3367/UFNe.0185.201504c.0371
URL: https://ufn.ru/en/articles/2015/4/c/
000357718100003
2-s2.0-84936750581
2015PhyU...58..345D
Citation: Doronina-Amitonova L V, Fedotov I V, Fedotov A B, Anokhin K V, Zheltikov A M "Neurophotonics: optical methods to study and control the brain" Phys. Usp. 58 345–364 (2015)
BibTexBibNote ® (generic)BibNote ® (RIS)MedlineRefWorks

Received: 25th, December 2014, 30th, December 2014

Оригинал: Доронина-Амитонова Л В, Федотов И В, Федотов А Б, Анохин К В, Жёлтиков А М «Нейрофотоника: оптические методы исследования и управления мозгом» УФН 185 371–392 (2015); DOI: 10.3367/UFNr.0185.201504c.0371

References (185) ↓ Cited by (45) Similar articles (20)

  1. Lakowicz J R Principles Of Fluorescence Spectroscopy (New York: Springer, 2006)
  2. Pawley J (Ed.) Handbook Of Biological Confocal Microscopy (New York: Springer, 2006)
  3. Turrell G, Corset J (Eds) Raman Microscopy: Developments And Applications (Amsterdam: Elsevier, 1996)
  4. Min W et al. Annu. Rev. Phys. Chem. 62 507 (2011)
  5. Evans C L, Xie X S Annu. Rev. Anal. Chem. 1 883 (2008)
  6. Denk W, Strickler J H, Webb W W Science 248 73 (1990)
  7. Hoover E E, Squier J A Nature Photon. 7 93 (2013)
  8. Horton N G et al. Nature Photon. 7 205 (2013)
  9. Débarre D et al. Nature Meth. 3 47 (2006)
  10. Witte S et al. Proc. Natl. Acad. Sci. USA 108 5970 (2011)
  11. O’Keefe J, Dostrovsky J Brain Res. 34 171 (1971)
  12. Hafting T et al. Nature 436 801 (2005)
  13. Chen L L et al. Exp. Brain Res. 101 8 (1994)
  14. Moser E I, Kropff E, Moser M-B Annu. Rev. Neurosci. 31 69 (2008)
  15. O’Keefe J, Moser M-B, Moser E I "The Nobel Prize in Physiology or Medicine 2014, Nobel Media AB 2014, Web 29 March 2015" http://www.nobelprize.org/nobel_prizes/medicine/laureates/2014/
  16. Betzig E. Hell S W, Moerner W E "The Nobel Prize in Chemistry 2014, Nobel Media AB 2014, Web 29 March 2015" http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2014/
  17. Knöpfel T, Boyden E S (Eds) Optogenetics. Tools For Controlling And Monitoring Neuronal Activity (Progress in Brain Research) Vol. 196 (Amsterdam: Elsevier, 2012)
  18. Holtmaat A et al. Nature Protocols 4 1128 (2009)
  19. Kerr J N D, Nimmerjahn A Curr. Opin. Neurobiol. 22 45 (2012)
  20. BernsteJ G. Garrity P A, Boyden E S Curr. Opin. Neurobiol. 22 61 (2012)
  21. Aravanis A M et al. J. Neural Eng. 4 S143 (2007)
  22. Doronina-Amitonova L V et al. Nature Sci. Rep. 3 3265 (2013)
  23. Kobat D, Horton N G, Xu C J. Biomed. Opt. 16 106014 (2011)
  24. Flusberg B A et al. Nature Meth. 2 941 (2005)
  25. Fu L, Gu M J. Microsc. 226 195 (2007)
  26. Brecht M et al. J. Neurosci. 24 9223 (2004)
  27. Kerr J N D, Denk W Nature Rev. Neurosci. 9 195 (2008)
  28. Callaghan P T Principles Of Nuclear Magnetic Resonance Microscopy (Oxford: Clarendon Press, 1993)
  29. Schmidt K C, Smith C B Nucl. Med. Biol. 32 719 (2005)
  30. Cohen D Science 175 664 (1972)
  31. Schulz D et al. Nature Meth. 8 347 (2011)
  32. Gabriel M Physiol. Behavior 12 145 (1974)
  33. Krüger J, Bach M Exp. Brain Res. 41 191 (1981)
  34. Wilt B A et al. Annu. Rev. Neurosci. 32 435 (2009)
  35. Yang G, Pan F, Gan W-B Nature 462 920 (2009)
  36. Stosiek C et al. Proc. Natl. Acad. Sci. USA 100 7319 (2003)
  37. Tian L et al. Nature Meth. 6 875 (2009)
  38. Djurisic M et al. J. Neurosci. 24 6703 (2004)
  39. Palmer L M, Stuart G J J. Neurosci. 29 6897 (2009)
  40. Chalfie M et al. Science 263 802 (1994)
  41. AnokhK V et al. Brain Res. 544 101 (1991)
  42. Boyden E S et al. Nature Neurosci. 8 1263 (2005)
  43. Zhang F et al. Nature Protocols 5 439 (2010)
  44. Zhang F et al. Nature Meth. 3 785 (2006)
  45. Liu X et al. Nature 484 381 (2012)
  46. Ji N et al. Curr. Opin. Neurobiol. 18 605 (2008)
  47. Shimomura O, Johnson F H, Saiga Y J. Cell. Compar. Physiol. 59 223 (1962)
  48. Prasher D C et al. Gene 111 229 (1992)
  49. Heim R, Prasher D C, Tsien R Y Proc. Natl. Acad. Sci. USA 91 12501 (1994)
  50. Ormö M et al. Science 273 1392 (1996)
  51. Cubitt A B et al. Trends Biochem. Sci. 20 448 (1995)
  52. Stepanenko O V i dr. Tsitologiya 49 395 (2007)
  53. Hill D K, Keynes R D J. Physiol. 108 278 (1949)
  54. Bouchard M B et al. Opt. Express 17 15670 (2009)
  55. Malonek D, Grinvald A Science 272 551 (1996)
  56. Stratonnikov A A, Loschenov V B J. Biomed. Opt. 6 457 (2001)
  57. Helmchen F Exp. Physiol. 87 737 (2002)
  58. Kawata S, Ohtsu M, Irie M (Eds) Nano-Optics (Springer Series in Optical Sciences) Vol. 84 (Berlin: Springer, 2002)
  59. Zipfel W R, Williams R M, Webb W W Nature Biotechnol. 21 1369 (2003)
  60. Helmchen F, Denk W Nature Meth. 2 932 (2005)
  61. Freudiger C W et al. Science 322 1857 (2008)
  62. Hell S W Nature Meth. 6 24 (2009)
  63. Bates M et al. Science 317 1749 (2007)
  64. Zheltikov A M Usp. Fiz. Nauk 177 737 (2007); Zheltikov A M Phys. Usp. 50 705 (2007)
  65. Flusberg B A et al. Nature Meth. 5 935 (2008)
  66. Doronina L V et al. Opt. Lett. 34 3373 (2009)
  67. Snyder A W, Love J D Optical Waveguide Theory (London: Chapman and Hall, 1983)
  68. Marcuse D J. Opt. Soc. Am. 68 103 (1978)
  69. Zheltikov A J. Opt. Soc. Am. B 22 1100 (2005)
  70. Russell P Science 299 358 (2003)
  71. Zheltikov A M Usp. Fiz. Nauk 170 1203 (2000); Zheltikov A M Phys. Usp. 43 1125 (2000)
  72. Nielsen M D et al. Opt. Lett. 28 2309 (2003)
  73. Akimov D A et al. Opt. Lett. 28 1948 (2003)
  74. Foster M, Moll K, Gaeta A Opt. Express 12 2880 (2004)
  75. Leon-Saval S et al. Opt. Express 12 2864 (2004)
  76. Foster M, Gaeta A Opt. Express 12 3137 (2004)
  77. Salem R et al. Nature Photon. 2 35 (2008)
  78. Foster M A et al. Nature 441 960 (2006)
  79. Foster M A et al. Nature 456 81 (2008)
  80. Levy J S et al. Nature Photon. 4 37 (2009)
  81. Knight J C Nature 424 847 (2003)
  82. Zheltikov A M Usp. Fiz. Nauk 174 73 (2004); Zheltikov A M Phys. Usp. 47 69 (2004)
  83. Birks T A, Knight J C, Russell P St J Opt. Lett. 22 961 (1997)
  84. Zheltikov A M Optika Mikrostrukturirovannykh Volokon (M.: Nauka, 2004)
  85. Fedotov A B et al. Appl. Phys. B 73 181 (2001)
  86. Zheltikov A M Usp. Fiz. Nauk 176 623 (2006); Zheltikov A M Phys. Usp. 49 605 (2006)
  87. Fedotov A B et al. Appl. Phys. B 77 313 (2003)
  88. Coen S et al. Opt. Lett. 26 1356 (2001)
  89. Ranka J K, Windeler R S, Stentz A J Opt. Lett. 25 25 (2000)
  90. Jones D J et al. Science 288 635 (2000)
  91. Udem T, Holzwarth R, Hänsch T W Nature 416 233 (2002)
  92. Hartl I et al. Opt. Lett. 26 608 (2001)
  93. Konorov S O i dr. Zh. Eksp. Teor. Fiz. 126 26 (2004); Konorov S O et al. JETP 99 19 (2004)
  94. Sidorov-Biryukov D A, Serebryannikov D A, Zheltikov A M Opt. Lett. 31 2323 (2006)
  95. Paulsen H N et al. Opt. Lett. 28 1123 (2003)
  96. von Vacano B, Wohlleben W, Motzkus M Opt. Lett. 31 413 (2006)
  97. Golovchenko E A i dr. Pis’ma ZhETF 42 74 (1985); Golovchenko E A et al. JETP Lett. 42 87 (1985)
  98. Mitschke F M, Mollenauer L F Opt. Lett. 11 659 (1986)
  99. Konorov S, Zheltikov A, Scalora M Opt. Express 13 3454 (2005)
  100. Myaing M T et al. Opt. Lett. 28 1224 (2003)
  101. Ye J Y et al. Proc. SPIE 5700 23 (2005)
  102. Fedotov I V et al. Appl. Opt. 48 5274 (2009)
  103. Fedotov I V i dr. Rossiiskie Nanotekhnologii 5 (3 - 4) 98 (2010); Fedotov I V et al. Nanotechnol. Russ. 5 266 (2010)
  104. Marcatili E A J, Schmeltzer R A Bell Syst. Tech. J. 43 1783 (1964)
  105. Russell P St J J. Lightwave Technol. 24 4729 (2006)
  106. Litchinitser N M et al. Opt. Lett. 27 1592 (2002)
  107. Litchinitser N M et al. Opt. Express 11 1243 (2003)
  108. Roberts P et al. Opt. Express 13 8277 (2005)
  109. Litchinitser N M, Poliakov E Appl. Phys. B 81 347 (2005)
  110. Zheltikov A M Nature Mater. 4 267 (2005)
  111. Doronina-Amitonova L V et al. Opt. Lett. 37 4642 (2012)
  112. Zheltikov A M Appl. Opt. 47 474 (2008)
  113. Zheltikov A M Usp. Fiz. Nauk 178 619 (2008); Zheltikov A M Phys. Usp. 51 591 (2008)
  114. Doronina-Amitonova L V et al. Appl. Phys. Lett. 98 253706 (2011)
  115. Tauer J et al. Laser Phys. Lett. 4 444 (2007)
  116. Konorov S O et al. Appl. Opt. 43 2251 (2004)
  117. Balciunas T et al. Nature Commun. 6 6117 (2015)
  118. Lanin A A et al. Appl. Phys. Lett. 100 101104 (2012)
  119. Yaroslavsky A N et al. Phys. Med. Biol. 47 2059 (2002)
  120. Ishimaru A Wave Propagation And Scattering In Random Media (New York: Academic Press, 1978); Isimaru A Rasprostranenie i Rasseyanie Voln v Sluchaino-neodnorodnykh Sredakh (M.: Mir, 1981)
  121. Doronina-Amitonova L V et al. Appl. Phys. Lett. 101 021114 (2012)
  122. Tai D C et al. J. Biomed. Opt. 12 034033 (2007)
  123. Schüz A, Palm G J. Compar. Neurol. 286 442 (1989)
  124. Fedotov I V et al. Appl. Phys. Lett. 104 083702 (2014)
  125. Helmchen F et al. Neuron 31 903 (2001)
  126. Flusberg B A et al. Opt. Lett. 30 2272 (2005)
  127. Göbel W et al. Opt. Lett. 29 2521 (2004)
  128. Sawinski J et al. Proc. Natl. Acad. Sci. USA 106 19557 (2009)
  129. Engelbrecht C J et al. Opt. Express 16 5556 (2008)
  130. Piyawattanametha W et al. Opt. Lett. 34 2309 (2009)
  131. Ghosh K K et al. Nature Meth. 8 871 (2011)
  132. Ziv Y et al. Nature Neurosci. 16 264 (2013)
  133. Barretto R P J et al. Nature Med. 17 223 (2011)
  134. Liang C et al. Appl. Opt. 41 4603 (2002)
  135. Carlson K et al. Appl. Opt. 44 1792 (2005)
  136. Rouse A R et al. Appl. Opt. 43 5763 (2004)
  137. Lane P M et al. Opt. Lett. 25 1780 (2000)
  138. Ota T et al. J. Biomed. Opt. 10 024010 (2005)
  139. Kleinfeld D et al. Proc. Natl. Acad. Sci. USA 95 15741 (1998)
  140. Nimmerjahn A et al. Nature Meth. 1 31 (2004)
  141. Theer P, Hasan M T, Denk W Opt. Lett. 28 1022 (2003)
  142. Mittmann W et al. Nature Neurosci. 14 1089 (2011)
  143. Kobat D et al. Opt. Express 17 13354 (2009)
  144. Doronina-Amitonova L V et al. J. Biophoton. 3 660 (2010)
  145. Vincent P et al. EMBO Rep. 7 1154 (2006)
  146. Bharali D J et al. Proc. Natl. Acad. Sci. USA 102 11539 (2005)
  147. Davenne M et al. Chem. Senses 30 (Suppl. 1) i115 (2005)
  148. Doronina-Amitonova L V et al. Appl. Phys. Lett. 101 233702 (2012)
  149. Yamaguchi S et al. Nature 409 684 (2001)
  150. Doronina-Amitonova L V et al. Appl. Phys. Lett. 102 161113 (2013)
  151. Doronina-Amitonova L V et al. 12th Intern. Conf. on Laser Applications in Life Sciences 2010, LALS-2010, Oulu, Finland, June 9 - 11, 2010, Technical Digest p. 124
  152. Doronina-Amitonova L V et al. Appl. Phys. Lett. 99 231109 (2011)
  153. Reintjes J F et al. Nonlinear Optical Parametric Processes In Liquids And Gases (New York: Academic Press, 1984)
  154. Squier J et al. Opt. Express 3 315 (1998)
  155. Campagnola P J, Loew L M Nature Biotechnol. 21 1356 (2003)
  156. Dombeck D A et al. Proc. Natl. Acad. Sci. USA 100 7081 (2003)
  157. Dombeck D A et al. J. Neurophysiol. 94 3628 (2005)
  158. Shneider M N, VoronA A, Zheltikov A M Phys. Rev. E 81 031926 (2010)
  159. Doronina-Amitonova L V et al. Appl. Phys. Lett. 103 093701 (2013)
  160. Chia S-H et al. Opt. Express 18 17382 (2010)
  161. Mizuno A et al. J. Raman Spectrosc. 25 25 (1994)
  162. Koljenović S et al. J. Biomed. Opt. 10 031116 (2005)
  163. Krafft C et al. Anal. Bioanal. Chem. 389 1133 (2007)
  164. Udovich J A et al. Appl. Opt. 47 4560 (2008)
  165. McCreery R L, Fleischmann M, Hendra P Anal. Chem. 55 146 (1983)
  166. Bergholt M S et al. J. Biophotonics 6 49 (2013)
  167. Krafft C et al. Biomed. Spectrosc. Imaging 1 39 (2012)
  168. Komachi Y et al. Appl. Opt. 48 1683 (2009)
  169. Doronina-Amitonova L V et al. Appl. Phys. Lett. 101 113701 (2012)
  170. Beier B D, Berger A J Analyst 134 1198 (2009)
  171. Ma J, Ben-Amotz D Appl. Spectrosc. 51 1845 (1997)
  172. Gift A D et al. J. Raman Spectrosc. 30 757 (1999)
  173. McClaB L, Jiaying, Ben-Amotz D Appl. Spectrosc. 53 1118 (1999)
  174. Dochow S et al. Opt. Express 20 20156 (2012)
  175. Komachi Y et al. Opt. Lett. 30 2942 (2005)
  176. Sato H et al. Vibration. Spectrosc. 50 125 (2009)
  177. Konorov S O et al. Opt. Lett. 31 1911 (2006)
  178. Evans C L et al. Opt. Express 15 12076 (2007)
  179. Voronin A A et al. Opt. Lett. 36 508 (2011)
  180. Evans C L et al. Proc. Natl. Acad. Sci. USA 102 16807 (2005)
  181. Fu Y et al. Opt. Express 16 19396 (2008)
  182. Légaré F et al. Opt Express 14 4427 (2006)
  183. Balu M et al. Opt. Express 18 2380 (2010)
  184. Saar B G et al. Science 330 1368 (2010)
  185. Saar B G et al. Opt. Lett. 36 2396 (2011)
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