On regularities in the spontaneous formation of structural hierarchies in chiral systems of nonliving and living matter

We review a general regularity observed in the spontaneous formation of alternating-sign L—D hierarchies of chiral structures that are initially unbalanced due to homochirality. Mechanical, hydrodynamic, macromolecular, and liquid-crystal systems, as well as proteins and nucleic acids, are considered. Biomacromolecule chirality is related to the presence of the asymmetric carbon atom and, further, to the formation of helical and superhelical intra- and supramolecular structures. Chirality is a physical vehicle that generates stratification and folding in biological macromolecular systems. The hierarchy of alternating-sign chiral structures underlies a periodic molecular biologic cell system.

Keywords: chirality, nucleic acids, proteins, hierarchy of structures, folding, molecular machines
PACS: 87.14.G−, 87.15.−v, 87.18.−h (all)
DOI: 10.3367/UFNe.2018.08.038401
URL: https://ufn.ru/en/articles/2019/4/c/
Web of Science

000472874200003
Scopus

2-s2.0-85072316118
ADS NASA

2019PhyU...62..354T
Citation: Tverdislov V A, Malyshko E V "On regularities in the spontaneous formation of structural hierarchies in chiral systems of nonliving and living matter" Phys. Usp. 62 354–363 (2019)

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Received: 13th, February 2018, revised: 21st, July 2018, accepted: 1st, August 2018

Оригинал: Твердислов В А, Малышко Е В «О закономерностях спонтанного формирования структурных иерархий в хиральных системах неживой и живой природы» УФН 189 375–385 (2019); DOI: 10.3367/UFNr.2018.08.038401

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