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Reviews of topical problems


Molecular energy transducers of the living cell. Proton ATP synthase: a rotating molecular motor

,
Lomonosov Moscow State University, Faculty of Physics, Leninskie Gory 1 build. 2, Moscow, 119991, Russian Federation

The free energy released upon the enzymatic hydrolysis of adenosine triphosphate (ATP) is the main source of energy for the functioning of the living cell and all multicellular organisms. The overwhelming majority of ATP molecules are formed by proton ATP synthases, which are the smallest macromolecular electric motors in Nature. This paper reviews the modern concepts of the molecular structure and functioning of the proton ATP synthase, and real-time biophysical experiments on the rotation of the ’rotor’ of this macromolecular motor. Some mathematical models describing the operation of this nanosized macromolecular machine are described.

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Fulltext is also available at DOI: 10.3367/UFNe.0180.201009b.0931
PACS: 87.10.−e, 87.15.−v, 87.16.−b (all)
DOI: 10.3367/UFNe.0180.201009b.0931
URL: https://ufn.ru/en/articles/2010/9/b/
000286041500002
2-s2.0-78751506517
2010PhyU...53..893R
Citation: Romanovsky Yu M, Tikhonov A N "Molecular energy transducers of the living cell. Proton ATP synthase: a rotating molecular motor" Phys. Usp. 53 893–914 (2010)
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Оригинал: Романовский Ю М, Тихонов А Н «Молекулярные преобразователи энергии живой клетки. Протонная АТФ-синтаза — вращающийся молекулярный мотор» УФН 180 931–956 (2010); DOI: 10.3367/UFNr.0180.201009b.0931

References (142) Cited by (53) ↓ Similar articles (20)

  1. Mukseev G N, Tikhonov A N BIOPHYSICS 70 (2) 189 (2025)
  2. Berdinskiy V L, Shevchenko U G Russ Chem Bull 74 (9) 2780 (2025)
  3. Matar I K, Fahimi P, Matta Ch F Pure and Applied Chemistry 97 (10) 1277 (2025)
  4. Yura N, Laptev A CCS 4 (2) 95 (2024)
  5. Manee M M, Al-Shomrani B M, Alqahtani F H Animals 14 (17) 2460 (2024)
  6. Churilova V V, Churilov G I et al Nanotechnol Russia 19 (5) 786 (2024)
  7. Tikhonov A N Photosynth Res 159 (2-3) 203 (2024)
  8. Churilov D G, Polishchuk S D et al Nanotechnol Russia 18 (3) 419 (2023)
  9. Benkov M A, Suslichenko I S et al Biochem. Moscow Suppl. Ser. A 17 (2) 92 (2023)
  10. Suslichenko I S, Benkov M A et al Biochem. Moscow Suppl. Ser. A 17 (2) 106 (2023)
  11. Tikhonov A N Biochemistry Moscow 88 (10) 1438 (2023)
  12. Tikhonov A N Biohimiâ 88 (10) 1742 (2023)
  13. Vigneau Je-N, Fahimi P et al Chem. Commun. 58 (16) 2650 (2022)
  14. Fahimi P, Matta Ch F Trends In Chemistry 4 (2) 96 (2022)
  15. Ustynyuk L Yu, Tikhonov A N Biochemistry Moscow 87 (10) 1084 (2022)
  16. Tikhonov A N Advances In Photosynthesis And Respiration Vol. Photosynthesis: Molecular Approaches to Solar Energy ConversionStructure-Function Relationships in Chloroplasts: EPR Study of Temperature-Dependent Regulation of Photosynthesis, an Overview47 Chapter 13 (2021) p. 343
  17. Riznichenko G Yu, Rubin A B Biol Bull Rev 11 (2) 93 (2021)
  18. Gulyaev Yu V, Bugaev A S et al Uspekhi Fizicheskikh Nauk 190 (04) 337 (2020)
  19. Eroshenko Yu N Uspekhi Fizicheskikh Nauk 190 (07) 762 (2020) [Eroshenko Yu N Phys.-Usp. 63 (7) 730 (2020)]
  20. Vershubskii A V, Tikhonov A N Biochem. Moscow Suppl. Ser. A 14 (2) 154 (2020)
  21. Tikhonov A N, Vershubskii A V Photosynth Res 146 (1-3) 299 (2020)
  22. Li H, Xie D-F et al Genes Genom 42 (5) 507 (2020)
  23. Rozenbaum V M, Shapochkina I V, Trakhtenberg L I Phys.-Usp. 62 (5) 496 (2019)
  24. Rozenbaum V M, Shapochkina I V, Trakhtenberg L I Uspekhi Fizicheskikh Nauk 189 (05) (2019)
  25. Rozenbaum V M, Shapochkina I V et al Phys. Rev. E 99 (1) (2019)
  26. Korochkova T Y, Shkoda N G et al Him. Fiz. Tehnol. Poverhni 10 (3) 227 (2019)
  27. Quapp W J Math Chem 56 (4) 1339 (2018)
  28. Vershubskii A V, Nevyantsev S M, Tikhonov A N Biochem. Moscow Suppl. Ser. A 12 (3) 287 (2018)
  29. Ustynyuk L Y, Tikhonov A N Journal Of Organometallic Chemistry 867 290 (2018)
  30. Xie D-F, Yu Ya et al IJMS 19 (7) 1847 (2018)
  31. Matta Ch F, Massa L J. Phys. Chem. A 121 (47) 9131 (2017)
  32. Vysotskaya U A, Shapochkina I V et al Him. Fiz. Tehnol. Poverhni 8 (3) 299 (2017)
  33. Ivontsin L A, Mashkovtseva E V, Nartsissov Ya R J. Phys.: Conf. Ser. 784 012021 (2017)
  34. Matta Ch F, Massa L Sustained Energy for Enhanced Human Functions and Activity (2017) p. 3
  35. Ivontsin L A, Mashkovtseva E V, Nartsissov Ya R J. Phys.: Conf. Ser. 917 042004 (2017)
  36. Nath S Biophysical Chemistry 219 69 (2016)
  37. Romanovsky Yu M, Trifonenkov V P Uspekhi Fizicheskikh Nauk 186 (2) 125 (2016)
  38. Ikryannikova L N, Ischenko D S et al Eur J Clin Microbiol Infect Dis 35 (1) 119 (2016)
  39. Kasumov E A, Kasumov R E, Kasumova I V Photosynth Res 123 (1) 1 (2015)
  40. Matta Ch F, Massa L Biochemistry 54 (34) 5376 (2015)
  41. Tikhonov A N Photosynth Res 125 (1-2) 65 (2015)
  42. Tikhonov A N, Vershubskii A V Biosystems 121 1 (2014)
  43. Kharchenko V O, Goychuk I Phys. Rev. E 87 (5) (2013)
  44. Chowdhury D Physics Reports 529 (1) 1 (2013)
  45. Tikhonov A N Photosynth Res 116 (2-3) 511 (2013)
  46. Romanovsky Yu M, Kargovsky A V, Ebeling W Eur. Phys. J. Spec. Top. 222 (10) 2465 (2013)
  47. Antipov A E, Zitserman V Yu, Makhnovskii Yu A Tech. Phys. 58 (11) 1563 (2013)
  48. Magdum S S NH 5 33 (2013)
  49. Krishtalik L I Uspekhi Fizicheskikh Nauk 182 (12) 1275 (2012)
  50. Pshenichnyuk S A, Asfandiarov N L, Kukhta A V Phys. Rev. A 86 (5) (2012)
  51. Makhnovskii Yu A, Zitserman V Yu, Antipov A E J. Exp. Theor. Phys. 115 (3) 535 (2012)
  52. Elenin G G, Aleksandrov P A Diff Equat 48 (7) 965 (2012)
  53. Tikhonov A N Biochemistry Moscow 77 (9) 956 (2012)
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