Reviews of topical problems

Quantum processes in biological molecules. Enzyme catalysis

Institute of Applied Physics, Academy of Sciences of Moldavia, Grosula str. 5, Kishinev, 277028, Moldavia

The oxidation-reduction enzymatic reaction is treated as a nonadiabatic multiquantum transition from the initial substrate-enzyme complex to a free product and free enzyme, taking into account the contribution of low-frequency (conformational) degrees of freedom of the enzyme molecule to the quantum transition described in terms of the reaction coordinate. It is demonstrated that the electromagnetic field has a marked effect on the enzymatic reaction rate by exciting low-frequency vibrations of enzyme molecules, a fact from which the nature of the so-called narrow biological resonances may be understood. A new mechanism giving rise to ultraviolet radiation from biological membranes is discussed. The theory can be used to explain the origin of ultraviolet radiation and dipole ordering of globular cell proteins.

Fulltext is available at IOP
PACS: 33.80.Rv, 87.10.+e, 87.15.−v, 82.50.−m (all)
DOI: 10.1070/PU1999v042n08ABEH000480
Citation: Kovarskii V A "Quantum processes in biological molecules. Enzyme catalysis" Phys. Usp. 42 797–815 (1999)
BibTexBibNote ® (generic)BibNote ® (RIS)MedlineRefWorks

Оригинал: Коварский В А «Квантовые процессы в биологических молекулах. Ферментативный катализ» УФН 169 889–908 (1999); DOI: 10.3367/UFNr.0169.199908c.0889

© 1918–2021 Uspekhi Fizicheskikh Nauk
Email: Editorial office contacts About the journal Terms and conditions