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Laser ion acceleration for hadron therapy

 a, b, c,  d,  b, c,  e,  f,  g,  d,  h
a Prokhorov General Physics Institute of the Russian Academy of Sciences, ul. Vavilova 38, Moscow, 119991, Russian Federation
b Kansai Photon Science Institute, Japan Atomic Energy Agency, 8-1-7 Umemidai, Kyoto, Kizugawa-shi, 619-0215, Japan
c Moscow Institute of Physics and Technology (National Research University), Institutskii per. 9, Dolgoprudny, Moscow Region, 141700, Russian Federation
d Technische Universität München, Boltzmann str. 3, München, 85748, Bundesrepublik Deutschland
e ELI-Beamlines, Institute of Physics, Czech Republic Academy of Sciences, Na Slovance 2, Prague, 18221, Czech Republic
f GSI Helmholtzzentrum für Schwerionenforschung GmbH, Plankstr 1, Darmstadt, 64291, Germany
g Forschungszentrum Dresden–Rossendorf, Institute of Radiochemistry, Dresden, Germany
h Russian Federation State Scientific Center ‘A.I. Alikhanov Institute of Theoretical and Experimental Physics’, ul. Bolshaya Cheremushkinskaya 25, Moscow, 117259, Russian Federation

The paper examines the prospects of using laser plasma as a source of high-energy ions for the purposes of hadron beam therapy — a possibility which is expected not only on theoretical grounds but also on experimental grounds (ions are routinely observed to be accelerated in the interaction of high-power laser radiation with matter). Compared to therapy accelerators like cyclotrons, laser technology is advantageous in that it is more compact and is simpler in delivering ions from the accelerator to the treatment room. Special target designs allow the radiation therapy requirements on ion beam quality to be satisfied.

Fulltext pdf (1.3 MB)
Fulltext is also available at DOI: 10.3367/UFNe.0184.201412a.1265
PACS: 41.75.Jv, 52.38.Kd, 87.50.−a, 87.53.Jw, 87.55.−x, 87.56.−v (all)
DOI: 10.3367/UFNe.0184.201412a.1265
URL: https://ufn.ru/en/articles/2014/12/a/
000350894500001
2-s2.0-84924357340
2014PhyU...57.1149B
Citation: Bulanov S V, Wilkens Ja J, Esirkepov T Zh, Korn G, Kraft G, Kraft S, Molls M, Khoroshkov V S "Laser ion acceleration for hadron therapy" Phys. Usp. 57 1149–1179 (2014)
BibTexBibNote ® (generic)BibNote ® (RIS)MedlineRefWorks

Received: 3rd, March 2014, 15th, July 2014

Оригинал: Буланов С В, Вилкенс Я Я, Есиркепов Т Ж, Корн Г, Крафт Г, Крафт С Д, Моллс М, Хорошков В С «Лазерное ускорение ионов для адронной терапии» УФН 184 1265–1298 (2014); DOI: 10.3367/UFNr.0184.201412a.1265

References (267) Cited by (134) ↓ Similar articles (20)

  1. Culfa O, Kim J et al Phys. Rev. E 113 (1) (2026)
  2. Lezhnin K V, Ospina-Bohórquez V et al Phys. Rev. Research 8 (3) (2026)
  3. Wei T, La n Z et al Nat Commun 17 (1) (2026)
  4. Amaducci S, Cosentino L et al Eur. Phys. J. Plus 141 (7) (2026)
  5. Kato Y, Mima K, Bulanov S Springer Series On Atomic, Optical, And Plasma Physics Vol. High Power Laser and Plasma ScienceLaser Ion Accelerators130 Chapter 25 (2026) p. 723
  6. Yan Ya, Huang M et al Phys. Rev. Accel. Beams 28 (3) (2025)
  7. Chen X, Yang L et al Eur. Phys. J. D 79 (4) (2025)
  8. Morita T Phys. Rev. E 112 (6) (2025)
  9. Wang W, Sun X et al Commun Phys 8 (1) (2025)
  10. Liu Z, Zhao M K et al AIP Advances 15 (5) (2025)
  11. Boller P, Hornung J et al Physics of Plasmas 32 (8) (2025)
  12. Korzhimanov A V QuBS 9 (1) 4 (2025)
  13. Pang Z, Liu J, Chen Z-Yu Physics of Plasmas 32 (10) (2025)
  14. Matys M, Hadjisolomou P et al New J. Phys. 27 (3) 033018 (2025)
  15. Matys M, Thistlewood Ja P et al Photonics 12 (5) 436 (2025)
  16. Guo X, Xu Sh et al High Pow Laser Sci Eng 13 (2025)
  17. Wang Z T, Yan Y H et al Phys. Scr. 100 (12) 125616 (2025)
  18. Gus’kov S Yu Physics of Plasmas 32 (1) (2025)
  19. Garten M, Bulanov S S et al Phys. Rev. Research 6 (3) (2024)
  20. Kim A, De y I et al Applied Sciences 15 (1) 237 (2024)
  21. Sakawa Y, Ishihara H et al Phys. Rev. Lett. 133 (19) (2024)
  22. Wei T, Arikawa Ya et al Physics of Plasmas 31 (7) (2024)
  23. Yan Ya, Yang T et al Phys. Rev. Accel. Beams 27 (5) (2024)
  24. Hakimi S, Bulanov S S et al Physics of Plasmas 31 (12) (2024)
  25. Bhadoria Sh, Marklund M, Keitel Ch H High Pow Laser Sci Eng 12 (2024)
  26. Yan Ya, Cheng H et al Phys. Rev. Accel. Beams 27 (5) (2024)
  27. Tazes I, Passalidis S et al Sci Rep 14 (1) (2024)
  28. Yang L, Wang X-N et al Acta Phys. Sin. 73 (11) 115202 (2024)
  29. Wang W Rev. Mod. Plasma Phys. 8 (1) (2024)
  30. Hata M, Sano T et al Phys. Rev. E 108 (3) (2023)
  31. Wang W P, Dong H et al Physics of Plasmas 30 (3) (2023)
  32. De Marco Sh Ch, Mondal S et al Matter and Radiation at Extremes 8 (5) (2023)
  33. Russell B K, Campbell P T et al Physics of Plasmas 30 (9) (2023)
  34. Sun X Y, Wang W P et al Plasma Phys. Control. Fusion 65 (9) 095008 (2023)
  35. Kovalev V F, Bychenkov V Yu Bull. Lebedev Phys. Inst. 50 (S7) S762 (2023)
  36. Matys M, Psikal Ja et al Photonics 10 (1) 61 (2023)
  37. Moon Je T, Bulanov S V et al Opt. Express 31 (13) 21614 (2023)
  38. Lü Jianfeng, Luo Yu ’? ’?р Chin. Sci. Bull. 68 (9) 1112 (2023)
  39. Ehret M, Apiñaniz Jon Imanol et al Nuclear Instruments And Methods In Physics Research Section B: Beam Interactions With Materials And Atoms 541 165 (2023)
  40. Paradkar B S Phys. Rev. E 108 (2) (2023)
  41. Marini S, Grech M et al Phys. Rev. Research 5 (1) (2023)
  42. Yan Ya, Yang T et al Nuclear Instruments And Methods In Physics Research Section A: Accelerators, Spectrometers, Detectors And Associated Equipment 1057 168737 (2023)
  43. Yan Ya, Yang T et al Chin. Sci. Bull. (2023)
  44. Gonoskov A, Blackburn T  G et al Rev. Mod. Phys. 94 (4) (2022)
  45. Hakimi S, Obst-Huebl L et al Physics of Plasmas 29 (8) (2022)
  46. Gabdrakhmanov I M, Govras E A Plasma Phys. Rep. 48 (2) 155 (2022)
  47. Wang W P, Dong H et al Applied Physics Letters 121 (21) (2022)
  48. Soni K K, Jain Sh et al Physics Letters A 426 127890 (2022)
  49. Morita T Phys. Rev. Research 4 (4) (2022)
  50. Chou H -G Jason, Grassi A et al J. Plasma Phys. 88 (6) (2022)
  51. Gong Zh, Bulanov S S et al Phys. Rev. Research 4 (4) (2022)
  52. Matys M, Bulanov S V et al New J. Phys. 24 (11) 113046 (2022)
  53. Davydov S G, Dolgov A N et al Plasma Phys. Rep. 48 (1) 59 (2022)
  54. Shi Y, Blackman D R et al High Pow Laser Sci Eng 10 (2022)
  55. Lezhnin K V, Bulanov S V Phys. Rev. Research 4 (3) (2022)
  56. Dolier E J, King M et al New J. Phys. 24 (7) 073025 (2022)
  57. Wan F, Wang W-Q et al Phys. Rev. Applied 17 (2) (2022)
  58. Shi Y, Blackman D et al Phys. Rev. Lett. 126 (23) (2021)
  59. Djordjević B Z, Kemp A J et al Physics of Plasmas 28 (4) (2021)
  60. Gelfer E G, Fedotov A M, Weber S New J. Phys. 23 (9) 095002 (2021)
  61. Bulanov S V Phys. Wave Phen. 29 (1) 1 (2021)
  62. Zhou W-Ju, Wang W-M, Chen L-M Plasma Phys. Control. Fusion 63 (3) 035016 (2021)
  63. Kumar R, Sakawa Y et al Phys. Rev. E 103 (4) (2021)
  64. Sakawa Y, Ohira Yu et al Phys. Rev. E 104 (5) (2021)
  65. Ma W-Ju, Liu Zh-P et al Acta Phys. Sin. 70 (8) 084102 (2021)
  66. Djordjević B Z, Kemp A J et al Plasma Phys. Control. Fusion 63 (9) 094005 (2021)
  67. Takagi Yu, Iwata N et al Phys. Rev. Research 3 (4) (2021)
  68. Culfa O, Sagir S J. Plasma Phys. 87 (6) (2021)
  69. Nedorezov V G, Rykovanov S G, Savel’ev A B Phys.-Usp. 64 (12) 1214 (2021)
  70. Culfa O Eur. Phys. J. D 75 (7) (2021)
  71. Alviri V M, Soleimani Sh A, Asem M M Advances In Intelligent Systems And Computing Vol. Proceedings of Fifth International Congress on Information and Communication TechnologyPlasma Temperature Classification for Cancer Treatment Based on Hadron Therapy1184 Chapter 2 (2021) p. 17
  72. Park J, Bin J H et al Physics of Plasmas 27 (12) (2020)
  73. Bailly-Grandvaux M, Kawahito D et al Phys. Rev. E 102 (2) (2020)
  74. Hadjisolomou P, Tsygvintsev I P et al Physics of Plasmas 27 (1) (2020)
  75. Matys M, Nishihara K et al High Energy Density Physics 36 100844 (2020)
  76. Culfa O, Sert V Indian J Phys 94 (9) 1451 (2020)
  77. Golovin D O, Mirfayzi S R et al High Energy Density Physics 36 100840 (2020)
  78. Morita T Plasma Phys. Control. Fusion 62 (10) 105003 (2020)
  79. Pae K H, Song H et al Plasma Phys. Control. Fusion 62 (5) 055009 (2020)
  80. Hadjisolomou P, Bulanov S V, Korn G J. Plasma Phys. 86 (3) (2020)
  81. Steinke S, Bin J  H et al Phys. Rev. Accel. Beams 23 (2) (2020)
  82. Scuderi V, Milluzzo G et al Nuclear Instruments And Methods In Physics Research Section A: Accelerators, Spectrometers, Detectors And Associated Equipment 978 164364 (2020)
  83. Nishiuchi M, Sakaki H et al Review of Scientific Instruments 91 (9) (2020)
  84. Nishiuchi M, Dover N P et al Phys. Rev. Research 2 (3) (2020)
  85. Park J, Bulanov S S et al Physics of Plasmas 26 (10) (2019)
  86. Cirrone G A P, Cuttone G et al Springer Proceedings In Physics Vol. Laser-Driven Sources of High Energy Particles and RadiationParticles Simulation Through Matter in Medical Physics Using the Geant4 Toolkit: From Conventional to Laser-Driven Hadrontherapy231 Chapter 9 (2019) p. 187
  87. Polz J, Robinson A P L et al Sci Rep 9 (1) (2019)
  88. Wang W, Jiang Ch et al High Pow Laser Sci Eng 7 (2019)
  89. Bin J H, Ji Q et al Review of Scientific Instruments 90 (5) (2019)
  90. Sangwan D, Culfa O et al Laser Part. Beams 37 (4) 346 (2019)
  91. Bulanov S V Rend. Fis. Acc. Lincei 30 (1) 5 (2019)
  92. Wang W P, Shen B F et al Physics of Plasmas 26 (4) (2019)
  93. Mackenroth F, Bulanov S S Physics of Plasmas 26 (2) (2019)
  94. Li Ju, Arefiev A V et al Sci Rep 9 (1) (2019)
  95. Milluzzo G, Scuderi V et al Review of Scientific Instruments 90 (8) (2019)
  96. Alviri V M, Soleimani Sh A et al Lecture Notes In Computer Science Vol. Computational Science and Its Applications ??I ICCSA 2019Particle Charging Using Ultra-Short Pulse Laser in the Ideal Maxwellian Cold Plasma for Cancer Treatment Based on Hadron Therapy11620 Chapter 61 (2019) p. 767
  97. Choudhary Sh, Holkundkar A R Physics of Plasmas 25 (10) (2018)
  98. Scuderi V, Amato A et al Applied Sciences 8 (9) 1415 (2018)
  99. Vy?l?en Lud?’k, Burian Tom?l?l ’? ’?р Radiation Research 189 (5) 466 (2018)
  100. Margarone D, Cirrone G et al QuBS 2 (2) 8 (2018)
  101. Macchi A, Livi C, Sgattoni A J. Inst. 12 (04) C04016 (2017)
  102. Wang Ch, Peng Y et al J Russ Laser Res 38 (4) 357 (2017)
  103. Cirrone G A P, Cuttone G et al Front. Oncol. 7 (2017)
  104. Bulanov S S, Bulanov S V et al (AIP Conference Proceedings) Vol. 1812 (2017) p. 090001
  105. Wang W P, Shen B F, Xu Z Z Physics of Plasmas 24 (1) (2017)
  106. Morita T Physics of Plasmas 24 (8) (2017)
  107. Romano F, Cirrone G A P et al J. Phys.: Conf. Ser. 777 012016 (2017)
  108. Jinno S, Tanaka H et al Opt. Express 25 (16) 18774 (2017)
  109. Makarov S, Pikuz S et al Opt. Express 25 (14) 16419 (2017)
  110. Yogo A, Mima K et al Sci Rep 7 (1) (2017)
  111. Bulanov S S, Beg F N (AIP Conference Proceedings) Vol. 1812 (2017) p. 030006
  112. Pikuz S A, Skobelev I Yu et al High Temp 54 (3) 428 (2016)
  113. Choudhary Sh, Holkundkar A R Eur. Phys. J. D 70 (11) (2016)
  114. Vay Je-L, Lehe Rémi Rev. Accl. Sci. Tech. 09 165 (2016)
  115. Nishiuchi M, Sakaki H et al Plasma Phys. Rep. 42 (4) 327 (2016)
  116. Romano F, Schillaci F et al Nuclear Instruments And Methods In Physics Research Section A: Accelerators, Spectrometers, Detectors And Associated Equipment 829 153 (2016)
  117. Margarone D, Velyhan A et al Phys. Rev. X 6 (4) (2016)
  118. Kim I J, Pae K H et al Physics of Plasmas 23 (7) (2016)
  119. Chukbar K V Plasma Phys. Rep. 42 (12) 1134 (2016)
  120. Yogo A, Bulanov S V et al Plasma Phys. Control. Fusion 58 (2) 025003 (2016)
  121. Lezhnin K V, Kamenets F F et al Physics of Plasmas 23 (5) (2016)
  122. Schillaci F, Cirrone G A P et al J. Inst. 11 (12) C12052 (2016)
  123. Yogo A Laser-Driven Particle Acceleration Towards Radiobiology and Medicine Biological And Medical Physics, Biomedical Engineering Chapter 11 (2016) p. 249
  124. Klenov G I, Khoroshkov V S ’pс’?’?kh’? ф’?’?’?ch’?с’?’?kh ’?’?у’? 186 (8) 891 (2016)
  125. Amato E, Italiano A et al Nuclear Instruments And Methods In Physics Research Section A: Accelerators, Spectrometers, Detectors And Associated Equipment 811 1 (2016)
  126. Gubin K V, Lotov K V et al Journal of Applied Physics 120 (11) (2016)
  127. Bulanov S S, Esarey E et al Physics of Plasmas 23 (5) (2016)
  128. Bulanov S  S, Esarey E et al Phys. Rev. ST Accel. Beams 18 (6) (2015)
  129. Bychenkov V Yu, Brantov A V et al ’pс’?’?kh’? ф’?’?’?ch’?с’?’?kh ’?’?у’? 185 (1) 77 (2015) [Bychenkov V Yu, Brantov A V et al Phys.-Usp. 58 (1) 71 (2015)]
  130. Lezhnin K V, Kamenets F F et al Physics of Plasmas 22 (3) (2015)
  131. Nishiuchi M, Sakaki H et al Physics of Plasmas 22 (3) (2015)
  132. (Laser Acceleration of Electrons, Protons, and Ions III; and Medical Applications of Laser-Generated Beams of Particles III) Vol. Laser Acceleration of Electrons, Protons, and Ions III; and Medical Applications of Laser-Generated Beams of Particles IIIMaximum attainable ion energy in the radiation pressure acceleration regimeKenneth W. D.LedinghamKlausSpohrPaulMcKennaPaul R.BoltonEricEsareyCarl B.SchroederFlorian J.GrünerS. S.BulanovE.EsareyC. B.SchroederS. V.BulanovT. Z.EsirkepovM.KandoF.PegoraroW. P.Leemans9514 (2015) p. 95140G
  133. Bulanov S  S, Esarey E et al Phys. Rev. Lett. 114 (10) (2015)
  134. (Research Using Extreme Light: Entering New Frontiers with Petawatt-Class Lasers II) Vol. Research Using Extreme Light: Entering New Frontiers with Petawatt-Class Lasers IITowards the effect of transverse inhomogeneity of electromagnetic pulse on the process of ion acceleration in the RPDA regimeGeorgKornLuis O.SilvaK. V.LezhninF. F.KamenetsV. S.BeskinM.KandoT. Z.EsirkepovS. V.Bulanov9515 (2015) p. 95151L
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