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Laser ion acceleration for hadron therapy

 a, b, c,  d,  b, c,  e,  f,  g,  d,  h
a Prokhorov General Physics Institute of the Russian Academy of Sciences, ul. Vavilova 38, Moscow, 119991, Russian Federation
b Kansai Photon Science Institute, Japan Atomic Energy Agency, 8-1-7 Umemidai, Kyoto, Kizugawa-shi, 619-0215, Japan
c Moscow Institute of Physics and Technology (National Research University), Institutskii per. 9, Dolgoprudny, Moscow Region, 141701, Russian Federation
d Technische Universität München, Boltzmann str. 3, München, 85748, Bundesrepublik Deutschland
e ELI-Beamlines, Institute of Physics, Czech Republic Academy of Sciences, Na Slovance 2, Prague, 18221, Czech Republic
f GSI Helmholtzzentrum für Schwerionenforschung GmbH, Plankstr 1, Darmstadt, 64291, Germany
g Forschungszentrum Dresden–Rossendorf, Institute of Radiochemistry, Dresden, Germany
h Russian Federation State Scientific Center ‘A.I. Alikhanov Institute of Theoretical and Experimental Physics’, ul. Bolshaya Cheremushkinskaya 25, Moscow, 117259, Russian Federation

The paper examines the prospects of using laser plasma as a source of high-energy ions for the purposes of hadron beam therapy — a possibility which is expected not only on theoretical grounds but also on experimental grounds (ions are routinely observed to be accelerated in the interaction of high-power laser radiation with matter). Compared to therapy accelerators like cyclotrons, laser technology is advantageous in that it is more compact and is simpler in delivering ions from the accelerator to the treatment room. Special target designs allow the radiation therapy requirements on ion beam quality to be satisfied.

Fulltext pdf (1.3 MB)
Fulltext is also available at DOI: 10.3367/UFNe.0184.201412a.1265
PACS: 41.75.Jv, 52.38.Kd, 87.50.−a, 87.53.Jw, 87.55.−x, 87.56.−v (all)
DOI: 10.3367/UFNe.0184.201412a.1265
URL: https://ufn.ru/en/articles/2014/12/a/
000350894500001
2-s2.0-84924357340
2014PhyU...57.1149B
Citation: Bulanov S V, Wilkens Ja J, Esirkepov T Zh, Korn G, Kraft G, Kraft S, Molls M, Khoroshkov V S "Laser ion acceleration for hadron therapy" Phys. Usp. 57 1149–1179 (2014)
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Received: 3rd, March 2014, 15th, July 2014

Оригинал: Буланов С В, Вилкенс Я Я, Есиркепов Т Ж, Корн Г, Крафт Г, Крафт С Д, Моллс М, Хорошков В С «Лазерное ускорение ионов для адронной терапии» УФН 184 1265–1298 (2014); DOI: 10.3367/UFNr.0184.201412a.1265

References (267) Cited by (121) ↓ Similar articles (20)

  1. Matys M, Hadjisolomou P et al New J. Phys. 27 033018 (2025)
  2. Yan Ya, Huang M et al Phys. Rev. Accel. Beams 28 (3) (2025)
  3. Gus’kov S Yu 32 (1) (2025)
  4. Korzhimanov A V QuBS 9 4 (2025)
  5. Bhadoria Sh, Marklund M, Keitel Ch H High Pow Laser Sci Eng 12 (2024)
  6. Sakawa Y, Ishihara H et al Phys. Rev. Lett. 133 (19) (2024)
  7. Wang W Rev. Mod. Plasma Phys. 8 (1) (2024)
  8. Wei T, Arikawa Ya et al 31 (7) (2024)
  9. Yan Ya, Yang T et al Phys. Rev. Accel. Beams 27 (5) (2024)
  10. Hakimi S, Bulanov S S et al 31 (12) (2024)
  11. Kim A, Dey I et al Applied Sciences 15 237 (2024)
  12. Yan Ya, Cheng H et al Phys. Rev. Accel. Beams 27 (5) (2024)
  13. Garten M, Bulanov S S et al Phys. Rev. Research 6 (3) (2024)
  14. Tazes I, Passalidis S et al Sci Rep 14 (1) (2024)
  15. Yang L, Wang X-N et al Acta Phys. Sin. 73 115202 (2024)
  16. Yan Ya, Yang T et al Chin. Sci. Bull. (2023)
  17. Paradkar B S Phys. Rev. E 108 (2) (2023)
  18. Marini S, Grech M et al Phys. Rev. Research 5 (1) (2023)
  19. Ehret M, Apiñaniz J I et al Nuclear Instruments And Methods In Physics Research Section B: Beam Interactions With Materials And Atoms 541 165 (2023)
  20. Kovalev V F, Bychenkov V Yu Bull. Lebedev Phys. Inst. 50 S762 (2023)
  21. Moon Je T, Bulanov S V et al Opt. Express 31 21614 (2023)
  22. Yan Ya, Yang T et al Nuclear Instruments And Methods In Physics Research Section A: Accelerators, Spectrometers, Detectors And Associated Equipment 1057 168737 (2023)
  23. Lü J, Luo Yu et al Chin. Sci. Bull. 68 1112 (2023)
  24. Hata M, Sano T et al Phys. Rev. E 108 (3) (2023)
  25. Matys M, Psikal Ja et al Photonics 10 61 (2023)
  26. De Marco Sh Ch, Mondal S et al 8 (5) (2023)
  27. Russell B K, Campbell P T et al 30 (9) (2023)
  28. Wang W P, Dong H et al 30 (3) (2023)
  29. Sun X Y, Wang W P et al Plasma Phys. Control. Fusion 65 095008 (2023)
  30. Matys M, Bulanov S V et al New J. Phys. 24 113046 (2022)
  31. Soni K K, Jain Sh et al Physics Letters A 426 127890 (2022)
  32. Davydov S G, Dolgov A N et al Plasma Phys. Rep. 48 59 (2022)
  33. Dolier E J, King M et al New J. Phys. 24 073025 (2022)
  34. Gong Zh, Bulanov S S et al Phys. Rev. Research 4 (4) (2022)
  35. Wan F, Wang W-Q et al Phys. Rev. Applied 17 (2) (2022)
  36. Chou H -G Jason, Grassi A et al J. Plasma Phys. 88 (6) (2022)
  37. Lezhnin K V, Bulanov S V Phys. Rev. Research 4 (3) (2022)
  38. Morita T Phys. Rev. Research 4 (4) (2022)
  39. Wang W P, Dong H et al 121 (21) (2022)
  40. Gonoskov A, Blackburn T  G et al Rev. Mod. Phys. 94 (4) (2022)
  41. Gabdrakhmanov I M, Govras E A Plasma Phys. Rep. 48 155 (2022)
  42. Hakimi S, Obst-Huebl L et al 29 (8) (2022)
  43. Shi Y, Blackman D R et al High Pow Laser Sci Eng 10 (2022)
  44. Zhou W-Ju, Wang W-M, Chen L-M Plasma Phys. Control. Fusion 63 035016 (2021)
  45. Djordjević B Z, Kemp A J et al Plasma Phys. Control. Fusion 63 094005 (2021)
  46. Culfa O Eur. Phys. J. D 75 (7) (2021)
  47. Djordjević B Z, Kemp A J et al 28 (4) (2021)
  48. Sakawa Y, Ohira Yu et al Phys. Rev. E 104 (5) (2021)
  49. Alviri V M, Soleimani Sh A, Asem M M Advances In Intelligent Systems And Computing Vol. Proceedings of Fifth International Congress on Information and Communication TechnologyPlasma Temperature Classification for Cancer Treatment Based on Hadron Therapy1184 Chapter 2 (2021) p. 17
  50. Nedorezov V G, Rykovanov S G, Savel’ev A B Phys.-Usp. 64 1214 (2021)
  51. Kumar R, Sakawa Y et al Phys. Rev. E 103 (4) (2021)
  52. Gelfer E G, Fedotov A M, Weber S New J. Phys. 23 095002 (2021)
  53. Takagi Yu, Iwata N et al Phys. Rev. Research 3 (4) (2021)
  54. Ma W-Ju, Liu Zh-P et al Acta Phys. Sin. 70 084102 (2021)
  55. Culfa O, Sagir S J. Plasma Phys. 87 (6) (2021)
  56. Shi Y, Blackman D et al Phys. Rev. Lett. 126 (23) (2021)
  57. Bulanov S V Phys. Wave Phen. 29 1 (2021)
  58. Nishiuchi M, Sakaki H et al 91 (9) (2020)
  59. Nishiuchi M, Dover N P et al Phys. Rev. Research 2 (3) (2020)
  60. Steinke S, Bin J  H et al Phys. Rev. Accel. Beams 23 (2) (2020)
  61. Hadjisolomou P, Bulanov S V, Korn G J. Plasma Phys. 86 (3) (2020)
  62. Scuderi V, Milluzzo G et al Nuclear Instruments And Methods In Physics Research Section A: Accelerators, Spectrometers, Detectors And Associated Equipment 978 164364 (2020)
  63. Hadjisolomou P, Tsygvintsev I P et al 27 (1) (2020)
  64. Park J, Bin J H et al 27 (12) (2020)
  65. Matys M, Nishihara K et al High Energy Density Physics 36 100844 (2020)
  66. Culfa O, Sert V Indian J Phys 94 1451 (2020)
  67. Pae K H, Song H et al Plasma Phys. Control. Fusion 62 055009 (2020)
  68. Golovin D O, Mirfayzi S R et al High Energy Density Physics 36 100840 (2020)
  69. Bailly-Grandvaux M, Kawahito D et al Phys. Rev. E 102 (2) (2020)
  70. Morita T Plasma Phys. Control. Fusion 62 105003 (2020)
  71. Mackenroth F, Bulanov S S 26 (2) (2019)
  72. Wang W P, Shen B F et al 26 (4) (2019)
  73. Polz J, Robinson A P L et al Sci Rep 9 (1) (2019)
  74. Bin J H, Ji Q et al 90 (5) (2019)
  75. Milluzzo G, Scuderi V et al 90 (8) (2019)
  76. Li Ju, Arefiev A V et al Sci Rep 9 (1) (2019)
  77. Bulanov S V Rend. Fis. Acc. Lincei 30 5 (2019)
  78. Sangwan D, Culfa O et al Laser Part. Beams 37 346 (2019)
  79. Cirrone G A P, Cuttone G et al Springer Proceedings In Physics Vol. Laser-Driven Sources of High Energy Particles and RadiationParticles Simulation Through Matter in Medical Physics Using the Geant4 Toolkit: From Conventional to Laser-Driven Hadrontherapy231 Chapter 9 (2019) p. 187
  80. Alviri V M, Soleimani Sh A et al Lecture Notes In Computer Science Vol. Computational Science and Its Applications – ICCSA 2019Particle Charging Using Ultra-Short Pulse Laser in the Ideal Maxwellian Cold Plasma for Cancer Treatment Based on Hadron Therapy11620 Chapter 61 (2019) p. 767
  81. Park J, Bulanov S S et al 26 (10) (2019)
  82. Wang W, Jiang Ch et al High Pow Laser Sci Eng 7 (2019)
  83. Choudhary Sh, Holkundkar A R 25 (10) (2018)
  84. Scuderi V, Amato A et al Applied Sciences 8 1415 (2018)
  85. Vyšín Luděk, Burian Tomáš et al Radiation Research 189 466 (2018)
  86. Margarone D, Cirrone G et al QuBS 2 8 (2018)
  87. Jinno S, Tanaka H et al Opt. Express 25 18774 (2017)
  88. Romano F, Cirrone G A P et al J. Phys.: Conf. Ser. 777 012016 (2017)
  89. Yogo A, Mima K et al Sci Rep 7 (1) (2017)
  90. Morita T 24 (8) (2017)
  91. Macchi A, Livi C, Sgattoni A J. Inst. 12 C04016 (2017)
  92. Cirrone G A P, Cuttone G et al Front. Oncol. 7 (2017)
  93. Bulanov S S, Bulanov S V et al (AIP Conference Proceedings) Vol. 1812 (2017) p. 090001
  94. Wang W P, Shen B F, Xu Z Z 24 (1) (2017)
  95. Wang Ch, Peng Y et al J Russ Laser Res 38 357 (2017)
  96. Bulanov S S, Beg F N (AIP Conference Proceedings) Vol. 1812 (2017) p. 030006
  97. Makarov S, Pikuz S et al Opt. Express 25 16419 (2017)
  98. Schillaci F, Cirrone G A P et al J. Inst. 11 C12052 (2016)
  99. Bulanov S S, Esarey E et al 23 (5) (2016)
  100. Nishiuchi M, Sakaki H et al Plasma Phys. Rep. 42 327 (2016)
  101. Pikuz S A, Skobelev I Yu et al High Temp 54 428 (2016)
  102. Amato E, Italiano A et al Nuclear Instruments And Methods In Physics Research Section A: Accelerators, Spectrometers, Detectors And Associated Equipment 811 1 (2016)
  103. Klenov G I, Khoroshkov V S Uspekhi Fizicheskikh Nauk 186 891 (2016)
  104. Choudhary Sh, Holkundkar A R Eur. Phys. J. D 70 (11) (2016)
  105. Vay Je-L, Lehe R Rev. Accl. Sci. Tech. 09 165 (2016)
  106. Yogo A Laser-Driven Particle Acceleration Towards Radiobiology and Medicine Biological And Medical Physics, Biomedical Engineering Chapter 11 (2016) p. 249
  107. Lezhnin K V, Kamenets F F et al 23 (5) (2016)
  108. Yogo A, Bulanov S V et al Plasma Phys. Control. Fusion 58 025003 (2016)
  109. Chukbar K V Plasma Phys. Rep. 42 1134 (2016)
  110. Gubin K V, Lotov K V et al 120 (11) (2016)
  111. Kim I J, Pae K H et al 23 (7) (2016)
  112. Margarone D, Velyhan A et al Phys. Rev. X 6 (4) (2016)
  113. Romano F, Schillaci F et al Nuclear Instruments And Methods In Physics Research Section A: Accelerators, Spectrometers, Detectors And Associated Equipment 829 153 (2016)
  114. Bulanov S  S, Esarey E et al Phys. Rev. Lett. 114 (10) (2015)
  115. Lezhnin K V, Kamenets F F et al 22 (3) (2015)
  116. Bulanov S  S, Esarey E et al Phys. Rev. ST Accel. Beams 18 (6) (2015)
  117. Bychenkov V Yu, Brantov A V et al Uspekhi Fizicheskikh Nauk 185 77 (2015)
  118. [Bychenkov V Yu, Brantov A V et al Phys.-Usp. 58 71 (2015)]
  119. Nishiuchi M, Sakaki H et al 22 (3) (2015)
  120. (Laser Acceleration of Electrons, Protons, and Ions III; and Medical Applications of Laser-Generated Beams of Particles III) Vol. Laser Acceleration of Electrons, Protons, and Ions III; and Medical Applications of Laser-Generated Beams of Particles IIIMaximum attainable ion energy in the radiation pressure acceleration regimeKenneth W. D.LedinghamKlausSpohrPaulMcKennaPaul R.BoltonEricEsareyCarl B.SchroederFlorian J.GrünerS. S.BulanovE.EsareyC. B.SchroederS. V.BulanovT. Z.EsirkepovM.KandoF.PegoraroW. P.Leemans9514 (2015) p. 95140G
  121. (Research Using Extreme Light: Entering New Frontiers with Petawatt-Class Lasers II) Vol. Research Using Extreme Light: Entering New Frontiers with Petawatt-Class Lasers IITowards the effect of transverse inhomogeneity of electromagnetic pulse on the process of ion acceleration in the RPDA regimeGeorgKornLuis O.SilvaK. V.LezhninF. F.KamenetsV. S.BeskinM.KandoT. Z.EsirkepovS. V.Bulanov9515 (2015) p. 95151L

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