An accelerator-based neutron source is developed for boron neutron capture therapy (BNCT) of oncological diseases. In the source, neutrons are produced through interaction of a proton beam accelerated in an electrostatic tandem accelerator, with a lithium target. The source generates an optimal neutron beam for BNCT treatment, and has several unique practical characteristics that make it ideally suited for clinical use. Namely, the tandem accelerator is compact (its design does not utilize accelerator tubes), reliable, simple and flexible in operation, as well as relatively inexpensive. The paper provides a comprehensive overview of the studies of the neutron source prototype and preliminary test results of the first specialized neutron source for clinical trials of BNCT.
Keywords: accelerator-based neutron source, electrostatic accelerator, boron neutron capture therapy, negative hydrogen ion source PACS:29.17.+w, 29.25.Dz, 87.19.xj, 87.53.−j, 87.53.Tf (all) DOI:10.3367/UFNe.2021.02.038940 Citation: Ivanov A A, Smirnov A N, Taskaev S Yu, Bayanov B F, Belchenko Yu I, Davydenko V I, Dunaevsky A, Emelev I S, Kasatov D A, Makarov A N, Meekins M, Kuksanov N K, Popov S S, Sanin A L, Sorokin I N, Sycheva T V, Shudlo I M, Vorob’ev D S, Cherepkov V G, Fadeev S N "Accelerator-based neutron source for boron neutron capture therapy" Phys. Usp., accepted
Received: 30th, March 2021, revised: 7th, April 2021, accepted: 8th, April 2021