The half-a-century development of radiobiological studies at the Joint Institute for Nuclear Research (JINR) is reviewed on a stage-by-stage basis. With the use of the Institute's accelerators, some key aspects of radiation biology have been settled, including the relative biological effectiveness (RBE) of radiations with different physical characteristics; the radiation-induced mutagenesis mechanisms; and the formation and repair of genetic structure damage. Practical space radiobiology problems that can be solved using high-energy charged particles are discussed.

Keywords: radiobiology, space radiobiology, the problem of the relative biological effectiveness, radiation-induced mutagenesis, repair damage, ionizing radiation PACS: 87.53.−j, 87.56.−v (all) DOI: 10.3367/UFNe.0186.201604e.0435 URL: https://ufn.ru/en/articles/2016/4/e/ 000379763700005 2-s2.0-84978472355 2016PhyU...59..411K Citation: Krasavin E A "Radiobiological research at JINR's accelerators" Phys. Usp. 59 411–418 (2016) BibTexBibNote ® (generic)BibNote ® (RIS)MedlineRefWorks Received: 6th, July 2015, accepted: 18th, August 2015 Оригинал: Красавин Е А «Радиобиологические исследования на ускорителях ОИЯИ» УФН 186 435–443 (2016); DOI: 10.3367/UFNr.0186.201604e.0435